CANCELLED- We will re-schedule and post the new date. Dr. Jennifer Swift, Professor and Chair, Department of Chemistry, Georgtown University
Dehydration of Molecular Hydrates
Fri, 9 February, 2024
10:00am - 11:00am
Dr. Jennifer Swift, Professor and Chair, Department of Chemistry, Georgetown University
The Department of Chemistry Presents: Dr. Jennifer Swift, Professor and Chair, Department of Chemistry, Georgetown University
Many pharmaceuticals can crystallize in hydrate and/or other solvate forms. While not all solvates have properties suitable for commercial development, they can serve as important precursor phases which, upon process-induced desolvation, yield crystal forms that may not be accessible through conventional growth methods. Yet predicting the products and mechanistic pathway(s) by which desolvation reactions occur remains a real challenge. Using a combination of time-resolved synchrotron PXRD and thermogravimetric methods, we will share insight into the mechanisms and molecular-level structural changes associated with the desolvation processes in select systems.
Research Interests
The Swift lab is broadly interested in understanding the nucleation, growth, phase changes and physical properties of molecular crystals. This research area has many direct applications to the medical, pharmaceutical, defense, and food-product industries. All projects are highly interdisciplinary, enabling students to gain valuable experience in at least a few different areas of chemistry and material science including x-ray crystallography, physical characterization methods, atomic force microscopy (AFM), organic synthesis, and/or computational modeling.
BIO
Jennifer Swift has spent the last 24 years on the faculty at Georgetown University where she is currently Vorisek Professor and the Chair of the Department of Chemistry. She earned her BA at Bowdoin (pronounced “BO Din”) College, her PhD at Yale University, and did a 2-year postdoc at the University of Minnesota. Her research group investigates crystallization mechanisms and structure-property relationships in a variety of molecular systems including those related to pharmaceuticals and crystal-deposition diseases such as gout and kidney stones.